Thermo Fisher Scientific CD157 Monoclonal Antibody (eBioSY11B5 (SY11B5)), PE, eBioscience

Applications

• Flow Cytometry (Flow): 5 µL (0.125 µg)/test
• View 3 publications

Product Specifications

Additional Formats

• Unconjugated
• Alexa Fluor 488
• APC
• NovaFluor Blue 660-120S
• NovaFluor Red 710
• NovaFluor Yellow 590
• NovaFluor Yellow 610
• PE-Cyanine7
• Super Bright 436
• Super Bright 600
• Request custom conjugation

Product Specific Information

The eBioSY11B5 monoclonal antibody recognizes human CD157 (Mo5, BST-1). CD157 is a 42–45 kDa, GPI-anchored protein structurally and functionally related to CD38. It is expressed on monocytes, macrophages, and bone marrow stromal cells, where it acts as an ectoenzyme and receptor involved in NAD⁺ metabolism and intracellular Ca²⁺ regulation. Upon ligand binding, CD157 may trigger phosphorylation of cytoplasmic proteins such as focal adhesion kinase (FAK).

Applications Reported: Flow cytometric analysis.
Applications Tested: Pre-titrated and validated for flow cytometry using normal human peripheral blood cells. Recommended use at 5 µL (0.125 µg) per 100 µL test volume. Suitable for 10⁵–10⁸ cells/test.
Excitation: 488–561 nm
Emission: 578 nm
Laser Compatibility: Blue, Green, Yellow-Green lasers
Filtration: 0.2 µm post-manufacturing filtered

Target Information

Bone marrow stromal cell antigen 1 (BST1) is a GPI-anchored molecule expressed by the BST1 gene in humans. It facilitates pre-B cell growth and acts as an ADP-ribosyl cyclase (DAMP-1). BST1 expression is elevated in bone marrow stromal cells from rheumatoid arthritis patients, potentially contributing to B cell abnormalities associated with the disease.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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