Thermo Fisher Scientific Phospho-Proteinase-Activated Receptor 2 (Thr375, Ser376) Polyclonal Antibody
인간 PAR2의 Thr375/Ser376 인산화 부위를 인식하는 Rabbit 폴리클로날 항체. Western blot에 1:1,000 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태. 연구용으로만 사용 가능.
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Applications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human PAR2 around the phosphorylation site of Thr375/Ser376 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins.
F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin, through proteolytic cleavage of its extracellular amino terminus.
The new amino terminus functions as a tethered ligand and activates the receptor.
The F2RL1 gene contains two exons and is widely expressed in human tissues.
The predicted protein sequence is 83% identical to the mouse receptor sequence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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