Thermo Fisher Scientific Epstein-Barr Virus (LMP-1) Monoclonal Antibody (CS4)
Epstein-Barr Virus(LMP-1)을 검출하는 Mouse monoclonal antibody(CS4). WB, IHC, ICC 등 다양한 응용 가능. 고순도 Protein A/G 정제, 200 µg/mL 농도. 연구용으로만 사용, 진단용 불가.
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Thermo Fisher Scientific Epstein-Barr Virus (LMP-1) Monoclonal Antibody (CS4)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1.0 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.5–1.0 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CS4 |
| Immunogen | Recombinant fusion protein containing bacterial beta-galactosidase and the carboxyl half of EBV-encoded LMP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Epstein-Barr virus (EBV) is a human herpes virus associated with conditions such as Hodgkin's disease and Burkitt's lymphoma, and is the causative agent of mononucleosis in adolescents. EBV latently infects B lymphocytes, which express EBV nuclear antigens and latent proteins LMP1, LMP2A, and LMP2B.
LMP2A aggregates in plasma membranes of B lymphocytes and negatively regulates Src and Syk protein tyrosine kinases. It blocks B-cell receptor (BCR) signal transduction in EBV-immortalized B cells and may help maintain latent EBV infection in peripheral blood B cells.
EBNA-1 is the only viral protein consistently expressed in all EBV-associated malignancies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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