Thermo Fisher Scientific JARID1C Polyclonal Antibody
JARID1C 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IP, ChIP-Seq 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제된 액상 항체로, 인간에 반응하며 Dog 및 Pig에도 예측 반응. 연구용으로만 사용.
- 판매단위
- pk
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Thermo Fisher Scientific JARID1C Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
| ChIP-sequencing (ChIP-Seq) | 1 µg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 275 and 325 of human Jumonji, AT rich interactive domain 1C |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Dog and Pig
Target Information
Serine/threonine kinase acting as a negative regulator of Ras-related Rap2-mediated signal transduction to control neuronal structure and AMPA receptor trafficking. Required for normal synaptic density, dendrite complexity, and surface AMPA receptor expression in hippocampal neurons. Activates JNK and MAPK14/p38 pathways and mediates stimulation of stress-activated MAPK14/p38 MAPK downstream of the Raf/ERK pathway. Phosphorylates TANC1 upon stimulation by RAP2A, MBP, and SMAD1. Plays an essential role in negative selection of thymocytes and regulation of actin cytoskeleton reorganization, cell-matrix adhesion, cell-cell adhesion, and cell migration.
Usage Restriction
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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