Thermo Fisher Scientific PDGF-BB Polyclonal Antibody
PDGF-BB 단백질을 인식하는 Thermo Fisher Scientific의 고트 폴리클로날 항체. Western blot, ELISA, 중화 및 억제 실험에 적합. 항원 친화 크로마토그래피로 정제된 액상 항체로, 인간 PDGF-BB에 반응. 연구용으로만 사용 가능.
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- PA124834
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Thermo Fisher Scientific PDGF-BB Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.2 µg/mL |
| ELISA | 0.5–1 µg/mL |
| Neutralization (Neu) | 0.025–0.2 µg/mL |
| Inhibition Assays (IA) | 0.025–0.200 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full-length human PDGF-BB protein expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 5% trehalose |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C and avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_795153 |
Product Specific Information
Neutralization: The ND50 is 0.025–0.200 µg/mL.
Target Information
The PDGF-BB protein is a member of the platelet-derived growth factor family, which includes four mitogenic factors for cells of mesenchymal origin characterized by eight cysteine motifs. PDGF-BB can form homodimers or heterodimers (PDGF-AB) connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7 involving this gene and COL1A1 are linked to dermatofibrosarcoma protuberans due to unregulated growth factor expression. Two alternatively spliced transcript variants encode different isoforms.
Usage Statement
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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