Thermo Fisher Scientific Arginase 1 Monoclonal Antibody (C7)
상품 옵션 정보 | ||||||||
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
MA550871 | - | Thermo Fisher Scientific MA550871 Arginase 1 Monoclonal Antibody (C7) 200 ul pk | 재고문의 | pk | 641,000원 | - | 705,100원 | |
MA550872 | - | Thermo Fisher Scientific MA550872 Arginase 1 Monoclonal Antibody (C7) 20 ul pk | 재고문의 | pk | 286,000원 | - | 314,600원 |
Applications
Tested Dilution
Publications
Western Blot (WB)
0.5-2 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
5-20 µg/mL
Immunocytochemistry (ICC/IF)
5-20 µg/mL
Product Specifications
Species Reactivity
Human, Pig
Host/Isotype
Mouse / IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
C7
Immunogen
Recombinant Human ARG protein, Met1-Lys322 (Accession #P05089) if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
Arginase 1,
uniProtId:
P05089-1,
ncbiNodeId:
9606,
antigenRange:
1-322,
antigenLength:
322,
antigenImageFileName:
MA5-50871_Arginase_1_P05089-1_House_mouse.svg,
antigenImageFileNamePDP:
MA5-50871_Arginase_1_P05089-1_House_mouse_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% Proclin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_3093437
Target Information
Arginase-1 (Arg1) is a 35 kDa enzyme converting L-arginine to urea and L-ornithine, which is the final step in the urea cycle. The resulting polyamines are important for cell proliferation and removal of toxins that arise from protein degradation. By degrading arginine, Arginase 1 deprives NO synthase of its substrate and down-regulates nitric oxide production. In both human and mouse, Arginase 1 is expressed in the liver, neutrophils, myeloid derived suppressor cells (MDSC) and neural stem cells. In human, expression in blood neutrophils but not in CCR3+ granulocytes has been reported. In mice, expression of Arginase 1 is one of the hallmarks of alternatively activated macrophages (M2a). Arginase-1 may be expressed in the myeloid cells infiltrating tumors, and is typically found in the majority of hepatocellular carcinomas. Defects in Arginase 1 are the cause of argininemia, an autosomal recessive disorder characterized by hyperammonemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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