Thermo Fisher Scientific LXR beta Monoclonal Antibody (5C11D3)
LXR beta 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, Western blot, ICC/IF, Flow cytometry 및 ELISA에 사용 가능. Human 시료 반응성. 1 mg/mL 농도의 액상 형태로 제공되며, 단백질 G 정제. 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | Assay-dependent |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5C11D3 |
| Immunogen | Purified recombinant fragment of human NR1H2 (AA: 1–200) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3091001 |
Target Information
Liver X receptors (LXRA and LXRB) are members of the nuclear receptor superfamily and play crucial roles in macrophage function, regulating transcriptional programs involved in lipid homeostasis and inflammation.
LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, while LXRB is ubiquitously expressed.
Ligand-activated LXRs form heterodimers with retinoid X receptors and regulate expression of target genes containing LXR response elements.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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