Thermo Fisher Scientific ICAM3 Monoclonal Antibody (OTI4G8), TrueMAB
ICAM3 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, Western blot에 최적화되어 있습니다. 인간 및 생쥐 시료에 반응하며, 고순도 친화 크로마토그래피로 정제되었습니다. PBS/BSA/glycerol 버퍼에 보관되며 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): 1:400–1:4,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4G8 |
| Immunogen | Full-length human recombinant ICAM3 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD50 (ICAM-3, intracellular adhesion molecule 3) is a transmembrane glycoprotein expressed by leukocytes and serves as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin. It mediates adhesion between T cells and antigen-presenting cells, regulates LFA-1 affinity for ICAM-1, and induces T cell activation and proliferation. ICAM-3 is essential in initiating immune responses and interacts with CD209 (DC-SIGN) on dendritic cells and macrophages, facilitating communication between dendritic cells and granulocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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