Thermo Fisher Scientific alpha Actinin 2 Polyclonal Antibody
Human alpha Actinin 2 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:500–1:1,000 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보존. 세포골격 단백질 연구용으로 적합.
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- PA582346
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- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ACTN2. Recombinant protein control fragment (Product # RP-102321) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2789505 |
Product Specific Information
Immunogen sequence:
AHEQFKATLP EADGERQSIM AIQNEVEKVI QSYNIRISSS NPYSTVTMDE LRTKWDKVKQ LVPIRDQSLQ EELARQHANE RLRRQFAAQA NAIGPWIQNK MEEIARSSIQ ITGALEDQMN QLKQYEHNII NYKNNIDKLE GD
Target Information
Alpha actinins belong to the spectrin gene superfamily, a diverse group of cytoskeletal proteins including alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in various cell types.
In nonmuscle cells, it is found along microfilament bundles and adherens-type junctions, where it binds actin to the membrane. In skeletal, cardiac, and smooth muscle cells, it localizes to the Z-disc and dense bodies, anchoring myofibrillar actin filaments.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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