Thermo Fisher Scientific GM-CSF Polyclonal Antibody
Thermo Fisher Scientific의 GM-CSF Polyclonal Antibody는 Mouse GM-CSF에 반응하는 Rabbit IgG 항체입니다. Western blot, ELISA, Functional assay에 사용 가능하며, 고순도 Affinity chromatography로 정제되었습니다. 연구용으로만 사용되며 장기 보관 시 -20°C에서 보관을 권장합니다.
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Thermo Fisher Scientific GM-CSF Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.2 µg/mL |
| ELISA | 0.5 µg/mL |
| Functional Assay | 12–20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant mouse GM-CSF |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1957018 |
Product Specific Information
Store as concentrated solution. Centrifuge briefly prior to opening vial.
Target Information
The GM-CSF gene encodes a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space.
This gene is located in a cluster of related genes at chromosome region 5q31, which is associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia.
Other genes in the cluster include interleukins 4, 5, and 13. The gene promotes tissue inflammation, and elevated cytokine levels have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome.
Mice lacking this gene or its receptor develop pulmonary alveolar proteinosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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