Thermo Fisher Scientific TIMP2 Polyclonal Antibody
TIMP2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 인간 TIMP2 중간 영역(aa 171-220)에서 유래한 합성 펩타이드를 면역원으로 사용했습니다. 다양한 종에서 높은 상동성을 보이며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human TIMP2 (aa 171–220) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2688567 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 79%
Target Information
TIMP-1 and TIMP-2 are inhibitory enzymes of the matrix metalloproteinase family and play an important role in maintaining connective tissue integrity.
TIMP-2 shows high binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (MMP-2 or gelatinase A) and also to the active form of 92 kDa Type IV collagenase (MMP-9 or gelatinase B).
TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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