
Thermo Fisher Scientific SDCBP Monoclonal Antibody (OTI2H6), TrueMAB
인간 SDCBP 단백질을 인식하는 Mouse monoclonal antibody로 Western blot과 IHC(P)에서 검증됨. Lyophilized 형태로 제공되며, PBS buffer(8% trehalose)로 안정화. 연구용으로 세포 신호전달, 세포골격 및 단백질 상호작용 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H6 |
| Immunogen | Full length human recombinant protein of human SDCBP produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The SDCBP (Syntenin 1) protein links syndecan-mediated signaling to the cytoskeleton. It contains tandem PDZ domains that interact with cytoplasmic domains of various transmembrane proteins.
This protein influences cytoskeletal organization, cell adhesion, protein trafficking, and transcription factor activation.
It is mainly localized at membrane-associated adherens junctions and focal adhesions, and also found in the endoplasmic reticulum and nucleus.
Alternative splicing results in multiple isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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