Thermo Fisher Scientific ITGA7 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ITGA7. Recombinant protein control fragment (Product #RP-88631). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ITGA7 (Integrin alpha 7),uniProtId:Q13683-1,ncbiNodeId:9606,antigenRange:92-185,antigenLength:1181,antigenImageFileName:PA5-52560_ITGA7_Integrin_alpha_7_Q13683-1_Rabbit.svg,antigenImageFileNamePDP:PA5-52560_ITGA7_Integrin_alpha_7_Q13683-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.30 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2642811

Product Specific Information

Immunogen sequence: FACPLSLEET DCYRVDIDQG ADMQKESKEN QWLGVSVRSQ GPGGKIVTCA HRYEARQRVD QILETRDMIG RCFVLSQDLA IRDELDGGEW KFCE

Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 91%.

Target Information

Integrin alpha-7 is a protein that in humans is encoded by the ITGA7 gene. This gene is mapped to 12q13.2. The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis. This protein functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in this gene are associated with congenital myopathy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.