Thermo Fisher Scientific OAS2 Monoclonal Antibody (OTI5E1), TrueMAB

Applications

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection.
The encoded protein is induced by interferons and uses ATP in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates.
These molecules activate latent RNase L, resulting in viral RNA degradation and inhibition of viral replication.
The three known members of this gene family are located in a cluster on chromosome 12.
Alternatively spliced transcript variants encoding different isoforms have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.