Thermo Fisher Scientific OAS2 Monoclonal Antibody (OTI5E1), TrueMAB
인간 OAS2 단백질(aa 60–335)에 특이적인 Mouse IgG2a 단일클론 항체로, Western blot 및 IHC(P)에서 검증됨. 무보존제, 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능. 바이러스 감염 관련 면역 반응 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5E1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 60–335 of human OAS2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection.
The encoded protein is induced by interferons and uses ATP in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates.
These molecules activate latent RNase L, resulting in viral RNA degradation and inhibition of viral replication.
The three known members of this gene family are located in a cluster on chromosome 12.
Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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