Thermo Fisher Scientific Contactin 2 Polyclonal Antibody
Contactin 2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC(P) 분석에 적합합니다. Rat 유래 합성 펩타이드(aa 550-600)를 면역원으로 사용하였으며, 신경세포 접착분자 연구에 활용됩니다. 동결건조 형태로 제공되며, 장기 보관 시 -20°C에서 보관하십시오.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 550–600 of rat Contactin 2 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The peptide is homologous in mouse.
- Specificity: Contactin-2.
Target Information
Contactin 2 (CNTN2), also known as transiently-expressed axonal glycoprotein (AXT, TAX, TAG-1, axonin 1), is a neuronal cell adhesion molecule (CAM) that influences axon connection formation during nervous system development.
It belongs to the immunoglobulin superfamily (IgSF) and includes:
- A glycosylphosphatidylinositol (GPI) anchor
- Six immunoglobulin (Ig)-like domains
- Four fibronectin type III (FNIII)-like domains
Contactin 2 is expressed predominantly during neural development on axonal membranes to guide commissural axons without promoting their growth.
It binds with NgCAM in the same membrane (cis-binding).
- Heterophilic binding sites (Contactin 2/NgCAM, Contactin 2/NrCAM): localized to the first four Ig domains
- Homophilic binding site (Contactin 2/Contactin 2): localized to the FNIII domain
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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