Thermo Fisher Scientific Gemin 3 Polyclonal Antibody
Gemin 3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 ICC/IF에 적합하며, 인간과 마우스 시료에서 반응. 고순도 Affinity chromatography 정제, 1 mg/mL 농도, 안정적 PBS/glycerol 저장용액 구성.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DDX20 (Accession Q9UHI6), corresponding to amino acid residues S272–A322 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851208 |
Product Specific Information
Antibody detects endogenous levels of total DDX20.
Target Information
Gemin 3 is a member of the DEAD box protein family characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD) and are putative RNA helicases. These proteins are involved in cellular processes that alter RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Some members of this family are associated with embryogenesis, spermatogenesis, and cellular growth and division. Gemin 3 exhibits ATPase activity and functions as a component of the survival of motor neurons (SMN) complex, playing a catalytic role in SMN complex function on RNPs. Dysfunction of Gemin 3 protein is linked to spinal muscular dystrophy and muscular atrophy.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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