
Thermo Fisher Scientific SMAD6 Monoclonal Antibody (5H3)
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Applications
Tested Dilution
Publications
Western Blot (WB)
1:500-1:2,000
ELISA (ELISA)
1:10,000
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse / IgG1
Class
Monoclonal
Type
Antibody
Clone
5H3
Immunogen
Purified recombinant fragment of human SMAD6 expressed in E. Coli.
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
ascites
Contains
0.03% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_10981633
Product Specific Information
MA5-15687 targets SMAD6 in indirect ELISA, WB applications and shows reactivity with Human samples.
The MA5-15687 immunogen is purified recombinant fragment of human SMAD6 expressed in E. Coli.
.
MA5-15687 detects SMAD6 which has a predicted molecular weight of approximately 53kDa.
Target Information
SMAD6 (mothers against decapentaplegic homolog 6) is an antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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