Thermo Fisher Scientific SMAD6 Monoclonal Antibody (5H3)
SMAD6 단백질을 인식하는 Mouse monoclonal antibody (Clone 5H3). Western blot과 ELISA에 적합하며 인간 샘플에 반응. 정제된 인간 SMAD6 재조합 단백질로부터 유래. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5H3 |
| Immunogen | Purified recombinant fragment of human SMAD6 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C for short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10981633 |
Product Specific Information
MA5-15687 targets SMAD6 in indirect ELISA and Western blot applications, showing reactivity with human samples.
The immunogen is a purified recombinant fragment of human SMAD6 expressed in E. coli.
MA5-15687 detects SMAD6 with a predicted molecular weight of approximately 53 kDa.
Target Information
SMAD6 (mothers against decapentaplegic homolog 6) is an antagonist of signaling by TGF-beta type I receptor superfamily members. It selectively inhibits BMP (bone morphogenetic protein) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is classified as an inhibitory SMAD (I-SMAD) or antagonistic SMAD.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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