Thermo Fisher Scientific TET3 Recombinant Rabbit Monoclonal Antibody (6I7Y2)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:2,000-1:20,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

6I7Y2

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-285 of mouse TET3 (Q8BG87). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TET3,uniProtId:Q8BG87-1,ncbiNodeId:10090,antigenRange:1-285,antigenLength:1803,antigenImageFileName:MA5-51207_TET3_Q8BG87-1_Rabbit.svg,antigenImageFileNamePDP:MA5-51207_TET3_Q8BG87-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.69 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_3093110

Product Specific Information

Immunogen sequence: MSQFQVPLAV QPDLSGLYDF PQGQVMVGGF QGPGLPMAGS ETQLRGGGDG RKKRKRCGTC DPCRRLENCG SCTSCTNRRT HQICKLRKCE VLKKKAGLLK EVEINAREGT GPWAQGATVK TGSELSPVDG PVPGQMDSGP VYHGDSRQLS TSGAPVNGAR EPAGPGLLGA AGPWRVDQKP DWEAASGPTH AARLEDAHDL VAFSAVAEAV SSYGALSTRL YETFNREMSR EAGSNGRGPR PESCSEGSED LDTLQTALAL ARHGMKPPNC TCDGPECPDF LEWLE

Target Information

TET3, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine and is most abundantly expressed in hematopoietic cells. Unlike the related TET2 protein, mutations in TET3 have not been observed in any myeloid malignancies. TET3 has been shown to be involved in the demethylation of zygotic DNA before the first mitosis and has been suggested to be involved in the epigenetic reprogramming of the zygotic paternal DNA following natural fertilization and may also contribute to somatic cell nuclear reprogramming during animal cloning.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.