Thermo Fisher Scientific Desmoglein 2 (DSG2) Polyclonal Antibody
Desmoglein 2(DSG2)에 특이적인 Rabbit Polyclonal Antibody로 인간, 마우스, 랫트 반응성. WB, IHC, ICC/IF, Flow Cytometry에 사용 가능. 항원 친화 크로마토그래피로 정제된 동결건조 형태로 -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.5–1 µg/mL | - |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | View 1 publication |
| Flow Cytometry (Flow) | 1–3 µg/1×10⁶ cells | - |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to C-terminus sequence of human Desmoglein 2 (1104–1118aa STRVTKHSTVQHSYS) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide, 0.05 mg thimerosal |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746287 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Desmosomes are cell-cell junctions found in epithelial, myocardial, and certain other cell types. Three desmoglein subfamily members are known, all belonging to the cadherin cell adhesion molecule superfamily. These genes are clustered on chromosome 18. Desmoglein 2 has been identified as the autoantigen in the autoimmune skin blistering disease pemphigus vulgaris.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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