Thermo Fisher Scientific EDN3 Polyclonal Antibody, MaxPab

Thermo Fisher Scientific EDN3 Polyclonal Antibody, MaxPab

Applications

• Western Blot (WB)

Tested Dilution: 1:1,000
Publications: -

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MEPGLWLLFG LTVTSAAGFV PCSQSGDAGR RGVSQAPTAA RSEGDCEETV AGPGEETVAG PGEGTVAPTA LQGPSPGSPG QEQAAEGAPE HHRSRRCTCF TYKDKECVYY CHLDIIWINT PEQTVPYGLS NYRGSFRGKR SAGPLPGNLQ LSHRPHLRCA CVGRYDKACL HFCTQTLDVS SNSRTAEKTD KEEEGKVEVK DQQSKQALDL HHPKLMPGSG LALAPSTCPR CLFQEGAP

Target Information

The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in various biological functions.
The active form of this protein is a 21 amino acid peptide processed from the precursor. It acts as a ligand for endothelin receptor type B (EDNRB), essential for development of neural crest-derived cell lineages such as melanocytes and enteric neurons.
Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS).
Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.