Thermo Fisher Scientific RSK1 Polyclonal Antibody
RSK1 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 사용 가능. 인간, 마우스, 원숭이, 랫트에 반응. 항원 친화 크로마토그래피로 정제되었으며, 보존제 무첨가 액상 형태. 세포 성장과 분화 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues surrounding Glu718 of human RSK1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 74 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11001738 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with the RSK2 or RSK3 isoforms.
Target Information
RPS6KA1 (RSK1) is a growth-factor regulated serine/threonine kinase involved in the MAPK cascade. It regulates cellular proliferation and differentiation through phosphorylation of transcription factors.
RPS6KA1 contains two nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the MAPK signaling pathway. Its activity is implicated in cell growth and differentiation control.
Alternate transcriptional splice variants encoding different isoforms have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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