Thermo Fisher Scientific ERAS Monoclonal Antibody (D10-B9)
인간 ERAS 단백질을 인식하는 Mouse IgG1 단클론 항체로, IHC(P) 및 ICC/IF에 적합합니다. 2 mg/mL 농도의 액상 제품이며 Protein A로 정제되었습니다. 연구용으로만 사용되며 4°C 또는 -20°C에서 보관 가능합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | D10-B9 |
| Immunogen | Recombinant protein within Human ERAS aa 1–233 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 40% Glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2802542 |
Target Information
The human ERAS gene was initially reported as a processed pseudogene (HRasp, Ha-Ras2), with several base substitutions in coding regions, but was later described as potentially encoding a functional human ERAS protein.
The ERAS oncogene supports tumorigenic growth of embryonic stem cells by producing a constitutively active Ras protein.
ERAS protein shares less than 50% amino acid identity with H-Ras, but retains key conserved domains essential for Ras function.
It contains amino acid residues identical to those present in active mutants of Ras and can cause oncogenic transformation in NIH 3T3 cells.
Human ERAS gene is localized in the chromosomal region Xp11.23.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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