Thermo Fisher Scientific MAP2K4 Polyclonal Antibody
MAP2K4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 최적화된 고품질 항체로, 항원 친화 크로마토그래피로 정제됨. 인간 MAP2K4에 반응하며 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MAP2K4. Recombinant protein control fragment (Product #RP-105147) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2791590 |
Product Specific Information
Immunogen sequence:
PAVSSMQGKR KALKLNFANP PFKSTARFTL NPNPTGVQNP HIERLRTHSI ESSGKLKISP EQHWDFTAED LKDLGEI
Target Information
MAP2K4 (MEK4) is a serine/threonine kinase of the STE7 family that phosphorylates and activates JNK1/2 and p38. It preferentially phosphorylates tyrosine residues of JNKs and mediates cellular stress and inflammatory cytokine responses.
MAP2K4 plays a role in carcinogenesis; loss-of-function mutations have been found in lung and pancreatic tumors, while a pro-oncogenic role has also been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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