Thermo Fisher Scientific ITGB1 Monoclonal Antibody (2B1)
Integrin beta-1D 단백질을 검출하는 Thermo Fisher Scientific의 ITGB1 단클론 항체(2B1). Western blot, IHC, ICC/IF에 적합하며, 인간, 개, 돼지, 생쥐 시료에서 반응. 고순도 정제된 액상 형태로 제공되며, 장기 보관 시 -20°C 권장.
- 카탈로그번호
- MA106906
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific ITGB1 Monoclonal Antibody (2B1)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:100–1:1,000 | - |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:25–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:25–1:200 | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Pig |
| Published Species | Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2B1 |
| Immunogen | Synthetic peptide corresponding to residues C Q(56) E N P I Y K S P I N N F K N P N Y G R K A G L(79) of mouse integrin beta 1D |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2128082 |
Product Specific Information
- MA1-06906 detects integrin beta-1D in human, canine, porcine, and mouse samples.
- Suitable for use in immunocytochemistry, immunohistochemistry, and Western blotting.
- Immunogen is a synthetic peptide corresponding to residues C Q(56) E N P I Y K S P I N N F K N P N Y G R K A G L(79) of the cytoplasmic domain of mouse integrin subunit β1D.
- Store at 4ºC or in small aliquots at -20ºC.
Target Information
ITGB1 (Integrin Subunit Beta 1, beta1 integrin subunit, GPIIa, CD29) is a 110 kDa cell surface glycoprotein widely expressed by various cells including all leukocytes.
It forms non-covalently linked heterodimers with multiple alpha chains (α1–α6), determining the binding properties of β1 (VLA) integrins.
ITGB1 functions as a cell adhesion molecule on platelets and is involved in interactions with extracellular matrix proteins.
Decreased ITGB1 expression correlates with multidrug resistance in tumor cells.
It plays a key role in immune cell trafficking, tissue damage regulation, and inflammatory responses such as in inflammatory bowel disease.
Two major isoforms exist: β1A (ubiquitous) and β1D (specific to cardiac and skeletal muscle).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.