Thermo Fisher Scientific METTL7A Monoclonal Antibody (OTI4B10)
METTL7A 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot과 IHC(P)에서 사용 가능. 인간 시료 반응성, Mouse IgG2a 형식. 고순도 친화 크로마토그래피 정제, 안정적 PBS/BSA/glycerol 완충액 보존.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4B10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 34–104 of METTL7A produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724680 |
Target Information
MettL7A belongs to the methyltransferase superfamily and is a probable methyltransferase. Methyltransferases transfer methyl groups from donors to acceptors, commonly on nucleic bases in DNA or amino acids in proteins. DNA methylation regulates gene expression without altering the DNA sequence and is essential for normal mammalian embryonic development. Disruption of methyltransferase genes can cause lethal phenotypes in mice. Aberrant methylation of tumor suppressor genes is associated with tumorigenesis and metastasis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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