Thermo Fisher Scientific SNRPA1 Polyclonal Antibody
SNRPA1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ELISA 등 다양한 응용 가능. 인간, 마우스, 랫트 반응성. 고순도 Affinity Chromatography 정제, 액상 형태로 안정적 보관 가능.
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Thermo Fisher Scientific SNRPA1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–220 of human SNRPA1 (NP_0030812) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.69 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804874 |
Product Specific Information
Immunogen sequence:
MVKLTAELIE QAAQYTNAVR DRELDLRGYK IPVIENLGAT LDQFDAIDFS DNEIRKLDGF PLLRRLKTLL VNNNRICRIG EGLDQALPCL TELILTNNSL VELGDLDPLA SLKSLTYLSI LRNPVTNKKH YRLYVIYKVP QVRVLDFQKV KLKERQEAEK MFKGKRGAQL AKDIARRSKT FNPGAGLPTD KKKGGPSPGD VEAIKNAIAN ASTLAEVERLPositive Samples: HT-29, Jurkat, Raji, HeLa, NIH/3T3, Mouse kidney, Mouse liver, Mouse lung
Cellular Location: Nucleus
Target Information
SNRPA1 (U2 snRNP-A) is located in gene map locus 15q26.3 and is a 28 kDa protein. It is a specific component of the U2 snRNP particle and consists of a unique N-terminal leucine-rich region and a hydrophobic RNA-binding C-terminal region. It lacks segments homologous to RNP1 and RNP2 motifs found in several RNA-binding proteins. SNRPA1 associates with U2 snRNP and participates in transcription and pre-mRNA splicing. It may play an important role in cell division and proliferation. Patients with connective tissue disorders often produce autoantibodies against snRNP particles.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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