Thermo Fisher Scientific beta Amyloid (1-42) Chimeric Recombinant Rabbit Monoclonal Antibody (21F12)
Thermo Fisher Scientific의 beta Amyloid (1-42) Chimeric Rabbit Monoclonal Antibody (21F12)은 인간 베타 아밀로이드(1-42) 서열을 인식하는 항체로, WB, IHC, ICC/IF, ELISA, IP 등 다양한 응용에 적합합니다. 단백질 A로 정제된 액상 형태이며, 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | Assay-dependent | |
| Immunohistochemistry (IHC) | Assay-dependent | |
| Immunocytochemistry (ICC/IF) | 1:1,000 | |
| ELISA | Assay-dependent | |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 21F12 |
| Immunogen | The original antibody was generated by immunizing A/J mice with a synthetic peptide (NH2-CYS-NH-CH2-(CH2)5-CO-GLMVGGVVIA-COOH) as an immunogen. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Product Specific Information
This antibody recognizes amino acids 33–42 of amyloid beta.
Target Information
Beta amyloid is a 40–43 amino acid peptide cleaved from amyloid precursor protein by gamma-secretase. Beta Amyloid (1–40) (Abeta 40) and Beta Amyloid (1–42) (Abeta 42) are two major C-terminal variants of amyloid beta protein, constituting the majority of amyloid beta species. Both forms are major components of extracellular plaques found in Alzheimer’s disease brain tissue.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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