Thermo Fisher Scientific OAS2 Monoclonal Antibody (OTI4B11), TrueMAB
인간 OAS2 단백질(aa 60-335)에 특이적인 mouse IgG1 단일클론 항체. Western blot에 최적화된 TrueMAB 포맷으로 제공. 동결건조 형태, PBS 버퍼 및 trehalose 포함. 연구용으로 바이러스 감염 관련 면역반응 연구에 적합.
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Applications
- Western Blot (WB)
Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4B11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 60–335 of human OAS2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional round of desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
OAS2 encodes a member of the 2-5A synthetase family, key proteins in the innate immune response to viral infection. The encoded protein is interferon-induced and catalyzes 2′-specific nucleotidyl transfer reactions to synthesize 2′,5′-oligoadenylates. These molecules activate RNase L, leading to viral RNA degradation and inhibition of viral replication.
Three family members are clustered on chromosome 12. Alternative splicing generates different isoforms.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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