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Thermo Fisher Scientific Phospho-Chk1 (Ser345) Recombinant Rabbit Monoclonal Antibody (Chk1S345-R3F9), PE
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Thermo Fisher Scientific Phospho-Chk1 (Ser345) Recombinant Rabbit Monoclonal Antibody (Chk1S345-R3F9), PE

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Phospho-Chk1 (Ser345) 인산화 단백질을 특이적으로 인식하는 재조합 토끼 단클론 항체. PE 형광 표지로 유세포분석(Flow Cytometry)에 적합. 인간, 마우스, 랫트 반응성. Protein A/G 정제, 4°C 보관.

카탈로그번호
MA537020
판매단위
pk
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마지막 업데이트 2025. 08. 04. 오전 04:29
Thermo Fisher Scientific MA537020 Phospho-Chk1 (Ser345) Recombinant Rabbit Monoclonal Antibody (Chk1S345-R3F9), PE 100 tests pk판매 단위 pk ·
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700,900원VAT 포함 770,990원

Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-Chk1 (Ser345) Recombinant Rabbit Monoclonal Antibody (Chk1S345-R3F9), PE

Applications

  • Flow Cytometry (Flow): 5 µL / 1×10⁶ cells

Product Specifications

항목 내용
Species Reactivity Human, Mouse, Rat
Host / Isotype Rabbit / IgG, kappa
Expression System HEK293 cells
Class Recombinant Monoclonal
Type Antibody
Clone Chk1S345-R3F9
Immunogen A synthetic phospho-peptide corresponding to residues surrounding Ser345 of human phospho Chk1
Conjugate PE
Excitation / Emission Max 565 / 576 nm
Form Liquid
Purification Protein A/G
Storage Buffer PBS with 0.20% BSA
Contains 0.09% sodium azide
Storage Conditions 4°C
Shipping Conditions Ambient (domestic); Wet ice (international)
RRID AB_2896955

Additional Formats

Target Information

CHEK1 (CHK1) is a serine/threonine protein kinase involved in preventing replication when DNA integrity is compromised. It is a key mediator in the DNA damage-induced checkpoint network and functions to ensure genomic integrity under genotoxic stress. Inhibition of CHK1 can lead to mitotic catastrophe in p53-deficient cancer cells, making CHK1 an attractive therapeutic target for cancer treatment, as approximately 50% of human cancers lack functional p53.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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