Thermo Fisher Scientific PPAT Monoclonal Antibody (OTI1C2), TrueMAB
PPAT 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western blot에 최적화됨. Human 시료 반응성, 비결합형 형태로 동결건조 상태 제공. 재구성 후 약 1 mg/mL 농도로 사용 가능하며, 연구용으로만 사용.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 42–278 of human PPAT produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The protein encoded by the PPAT gene belongs to the purine/pyrimidine phosphoribosyltransferase family. It acts as a regulatory allosteric enzyme catalyzing the first step of de novo purine nucleotide biosynthesis.
This gene and PAICS/AIRC, a bifunctional enzyme involved in steps six and seven of the same pathway, are located in close proximity on chromosome 4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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