Thermo Fisher Scientific HCN1 Polyclonal Antibody
HCN1 단백질을 인식하는 Thermo Fisher Scientific의 양친매성 폴리클로날 항체로, 인간·마우스·랫트에 반응합니다. WB 및 IHC에 사용 가능하며, 합성 펩타이드 면역원으로 제작되었습니다. 연구용으로만 사용되며 안정적 장기 보관이 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:300–1:2,000
- Publications: View 2 publications
Immunohistochemistry (IHC)
- Tested Dilution: 1:300–1:2,000
- Publications: View 2 publications
Miscellaneous PubMed (Misc)
- Publications: View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Sheep / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from cytoplasmic region of human HCN1 conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The antigen is homologous in many species including mouse and rat.
- Specificity: HCN1.
Target Information
HCN1 (Hyperpolarization-activated cation channel 1) belongs to the HCN gene family, contributing to spontaneous rhythmic activity in both heart and brain.
HCN1 and HCN2 are important for motor learning and neuronal integration by cerebellar Purkinje cells, shaping autonomous neuronal activity and network oscillations.
HCN1 expression is enriched in cerebral cortex, hippocampus, cerebellum, and facial motor nucleus.
HCN2 is abundant in mamillary bodies, pontine nucleus, ventral cochlear nucleus, and nucleus of the trapezoid body.
Regional specificity of HCN channels contributes to differences in neuronal pacemaker activity across brain systems.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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