Thermo Fisher Scientific DRD2 Polyclonal Antibody
DRD2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태로 -20°C 보관.
- 카탈로그번호
- PA5115142
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DRD2 (Accession P14416), corresponding to amino acid residues L252–H302 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899778 |
Product Specific Information
Antibody detects endogenous levels of total DRD2.
Target Information
The DRD2 Dopamine Receptor is involved in neuromodulation of appetitive behaviors. DRD2 may be linked to alcoholism and other substance-use disorders. Mutations in DRD2 in mice lead to suppression of reward behavior with morphine and reduction of spontaneous movements, resembling Parkinson’s disease. Three alternatively spliced isoforms have been identified. DRD2 is expressed in various regions of the brain, aorta, artery, eye, and spinal cord. ESTs have been isolated from normal pituitary and in brain, colon, lung, pancreas, and skeletal muscle cancer libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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