
ELK Biotechnology Claudin-3 (phospho Tyr219) rabbit pAb
Claudin-3 (phospho Tyr219) rabbit polyclonal antibody로 tight junction 관련 단백질 연구에 적합. WB, IHC, IF, ELISA 등 다양한 실험에 사용 가능. 인간, 쥐, 생쥐 반응성 확인. 고순도 IgG, 1 mg/ml 농도, -20°C에서 1년 안정적 보관.
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Claudin-3 (phospho Tyr219) Rabbit Polyclonal Antibody
제품 개요
ELK Biotechnology에서 제공하는 Claudin-3 (phospho Tyr219) rabbit pAb는 세포 간 접합부(tight junction) 연구에 사용되는 고품질 항체입니다. Claudin-3 단백질의 Tyr219 인산화 부위를 인식하며, 다양한 응용 분야에서 활용 가능합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product Name | Claudin-3 (phospho Tyr219) rabbit pAb |
| Alternative Names | CLDN3; C7orf1; CPETR2; Claudin-3; Clostridium perfringens enterotoxin receptor 2; CPE-R 2; CPE-receptor 2; Rat ventral prostate.1 protein homolog; hRVP1 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human Claudin-3 around phosphorylation site of Tyr219 (AA range: 171–220) |
| Species Reactivity | Human; Rat; Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 28 kD |
| Gene ID (Human) | 1365 |
| Human Swiss-Prot No. | O15551 |
| Cellular Localization | Cell junction, tight junction; Cell membrane; Multi-pass membrane protein |
| Storage | -20°C, 1 year |
| Host Species | Rabbit |
Background
Tight junctions are specialized structures that facilitate cell-to-cell adhesion in epithelial or endothelial sheets, forming continuous seals around cells to regulate paracellular permeability. Claudin-3 is an integral membrane protein and a key component of tight junction strands. It also functions as a low-affinity receptor for Clostridium perfringens enterotoxin and shares sequence similarity with a putative apoptosis-related protein found in rat.
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