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ELK Biotechnology Claudin-4 (phospho Tyr208) rabbit pAb
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Claudin-4 단백질의 Tyr208 인산화 부위를 인식하는 토끼 폴리클로날 항체로, IHC, IF, ELISA에 적합합니다. 세포막 타이트 정션 단백질 연구에 활용되며, 인간, 랫, 마우스 시료에 반응합니다. -20°C에서 1년 보관 가능합니다.
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- pk
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ELK Biotechnology ES4788-100UL Claudin-4 (phospho Tyr208) rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES4788-50UL Claudin-4 (phospho Tyr208) rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology Claudin-4 (phospho Tyr208) rabbit pAb
Claudin-4 (phospho Tyr208) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Claudin-4 (phospho Tyr208) rabbit pAb |
| Alternative Names | CLDN4; CPER; CPETR1; WBSCR8; Claudin-4; Clostridium perfringens enterotoxin receptor; CPE-R; CPE-receptor; Williams-Beuren syndrome chromosomal region 8 protein |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | Immunohistochemistry: 1/100 - 1/300 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Claudin 4 around the phosphorylation site of Tyr208 (AA range: 160–209) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 1364 |
| Human Swiss-Prot No | O14493 |
| Species Reactivity | Human; Rat; Mouse |
| Cellular Localization | Cell junction, tight junction; Cell membrane; Multi-pass membrane protein. CLDN4 is required for tight junction localization in the kidney. |
Background
The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of epithelial cell tight junctions, regulating the movement of solutes and ions through the paracellular space. This protein serves as a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.
(Provided by RefSeq, Sep 2013)
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