ELK Biotechnology Histone H4 (phospho Ser47) rabbit pAb
Histone H4의 Ser47 인산화 부위를 인식하는 토끼 폴리클로날 항체. WB, IF, IHC, ELISA에 사용 가능. 핵 및 염색체에 위치한 단백질 검출에 적합. 인간, 마우스, 랫트 반응성.
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Histone H4 (phospho Ser47) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Histone H4 (phospho Ser47) rabbit pAb |
| Alternative Names | HIST1H4A; H4/A; H4FA; HIST1H4B; H4/I; H4FI; HIST1H4C; H4/G; H4FG; HIST1H4D; H4/B; H4FB; HIST1H4E; H4/J; H4FJ; HIST1H4F; H4/C; H4FC; HIST1H4H; H4/H; H4FH; HIST1H4I; H4/M; H4FM; HIST1H4J; H4/E; H4FE; HIST1H4K; H4/D; H4FD; HIST1H4L; H4/K; H4FK |
| Applications | IF, IHC, WB, ELISA |
| Recommended Dilutions | WB: 1:500–1:2000 Immunofluorescence: 1:200–1:1000 ELISA: 1:5000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human Histone H4 around the phosphorylation site of Ser47 (AA range: 13–62) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 13 kDa |
| Gene ID (Human) | 121504, 554313, 8294, 8359, 8360, 8361, 8362, 8363, 8364, 8365, 8366, 8367, 8368, 8370 |
| Human Swiss-Prot No. | P62805 |
| Cellular Localization | Nucleus, Chromosome |
| Species Reactivity | Human, Mouse, Rat |
Background
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes.
The linker histone H1 interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher-order structures.
This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. (RefSeq, Aug 2015)
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