ELK Biotechnology Atg4A rabbit pAb
Human 및 Mouse에서 반응하는 Atg4A 단백질에 대한 rabbit polyclonal antibody. WB, IHC, IF, ELISA 등 다양한 응용 가능. 합성 human ATG4A 펩타이드(AA 81-130)를 면역원으로 사용. 세포질에 위치하며 자가포식 관련 연구에 적합.
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제품명
Atg4A rabbit pAb
공급업체
ELK Biotechnology
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | ATG4A; APG4A; AUTL2; Cysteine protease ATG4A; AUT-like 2 cysteine endopeptidase; Autophagin-2; Autophagy-related cysteine endopeptidase 2; Autophagy-related protein 4 homolog A; hAPG4A |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 Immunofluorescence: 1/200 - 1/1000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human ATG4A (AA range: 81–130) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 115201 |
| Human Swiss-Prot No | Q8WYN0 |
| Cellular Localization | Cytoplasm |
| Species Reactivity | Human; Mouse |
Background
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. It is essential for cell homeostasis and remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, suggesting a role in controlling unregulated cell growth linked to cancer.
This gene encodes a member of the autophagin protein family, also designated as a member of the C-54 family of cysteine proteases.
[provided by RefSeq, Mar 2016]
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