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ELK Biotechnology A Cyclase VIII rabbit pAb
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ELK Biotechnology A Cyclase VIII rabbit pAb

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ADCY8 단백질을 인식하는 토끼 폴리클로날 항체로 IHC, IF, ELISA에 사용 가능. 인간, 마우스, 랫트 시료에 반응. 세포막 및 시냅스 부위에 주로 존재하는 단백질 검출에 적합. -20°C에서 1년 보관 가능.

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ELK Biotechnology ES4642-100UL A Cyclase VIII rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES4642-50UL A Cyclase VIII rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology A Cyclase VIII rabbit pAb

제품명

A Cyclase VIII rabbit pAb

공급업체

ELK Biotechnology

제품 정보

항목 내용
Alternative Names ADCY8; Adenylate cyclase type 8; ATP pyrophosphate-lyase 8; Adenylate cyclase type VIII; Adenylyl cyclase 8; AC8; Ca(2+)/calmodulin-activated adenylyl cyclase
Applications IHC; IF; ELISA
Recommended Dilutions Immunohistochemistry: 1/100 - 1/300
Immunofluorescence: 1/200 - 1/1000
ELISA: 1/40000
Not yet tested in other applications
Immunogen Synthesized peptide derived from human ADCY8 (AA range: 591–640)
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
GeneID (Human) 114
Human Swiss-Prot No P40145
Species Reactivity Human; Mouse; Rat

세포 내 위치 (Cellular Localization)

Cell membrane; Multi-pass membrane protein; Basolateral cell membrane; Apical cell membrane; Cell junction (synapse); Cell projection (dendrite, axon); Presynaptic cell membrane; Postsynaptic density; Membrane raft; Clathrin-coated vesicle membrane; Caveola.
Monomeric N-glycosylated species localize in membrane raft; unglycosylated forms are enriched in clathrin-coated pits and vesicles. Dimers are localized outside membrane rafts. Membrane raft localization and integrity are indispensable for CCE-stimulated adenylate cyclase activity.

배경 (Background)

Adenylate cyclase is a membrane-bound enzyme that catalyzes the formation of cyclic AMP from ATP. Its enzymatic activity is regulated by several hormones, and signal transduction involves G proteins (Gs and Gi) that modulate the catalytic subunit of adenylyl cyclase.
[Provided by RefSeq, Jul 2008]

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