
ELK Biotechnology CysLTR1 rabbit pAb
CysLTR1 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간 및 원숭이에 반응하며, 세포막 단백질 검출에 적합. 천식 및 암 관련 연구에 활용 가능.
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제품명
CysLTR1 rabbit pAb
제품 개요
CysLTR1 단백질에 특이적인 토끼 폴리클로날 항체입니다. 인간 및 원숭이 시료에서 반응하며, Western blot, Immunohistochemistry, Immunofluorescence, ELISA 등 다양한 실험에 활용할 수 있습니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | CysLTR1 rabbit pAb |
| Alternative Names | CYSLTR1; CYSLT1; Cysteinyl leukotriene receptor 1; CysLTR1; Cysteinyl leukotriene D4 receptor; LTD4 receptor; G-protein coupled receptor HG55; HMTMF81 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 IF: 1/200–1/1000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human CLTR1 (AA range: 131–180) |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 36 kD |
| Gene ID (Human) | 10800 |
| Human Swiss-Prot No | Q9Y271 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein |
| Species Reactivity | Human; Monkey |
| Storage | -20°C / 1 year |
Background
This gene encodes a member of the G-protein coupled receptor 1 family. The encoded protein is a receptor for cysteinyl leukotrienes and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of this gene is associated with asthma, and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants.
(Provided by RefSeq, Aug 2013)
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