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ELK Biotechnology TIP60 rabbit pAb
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TIP60 단백질에 특이적인 토끼 폴리클로날 항체로, IHC, IF, ELISA에 사용 가능. 인간 및 생쥐 시료 반응성. 핵 및 세포질 내 TIP60 단백질 검출에 적합하며, DNA 수선 및 전사 조절 연구에 유용.
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ELK Biotechnology ES4497-100UL TIP60 rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES4497-50UL TIP60 rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology TIP60 rabbit pAb
제품명
TIP60 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | KAT5; HTATIP; TIP60; Histone acetyltransferase KAT5; 60 kDa Tat-interactive protein; Tip60; Histone acetyltransferase HTATIP; HIV-1 Tat interactive protein; Lysine acetyltransferase 5; cPLA(2)-interacting protein |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | Immunohistochemistry: 1/100–1/300 Immunofluorescence: 1/200–1/1000 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TIP60 (AA range: 52–101) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 10524 |
| Human Swiss-Prot No. | Q92993 |
| Species Reactivity | Human; Mouse |
| Cellular Localization | Nucleus, Chromosome, Cytoplasm, Chromosome (centromere, kinetochore), Cytoskeleton (spindle pole), Nucleolus, Perinuclear region. Upon stimulation with EDN1, exported from nucleus to perinuclear region; UV irradiation induces translocation into nuclear bodies (PubMed:11262386). Transiently localizes to kinetochores in early mitosis (PubMed:26829474). Localizes to spindle poles during metaphase (PubMed:34608293). Found in cytoplasm and nucleus of round spermatids (By similarity). |
| Background | The protein encoded by this gene belongs to the MYST family of histone acetyltransferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs regulate chromatin remodeling, transcription, and other nuclear processes by acetylating histone and non-histone proteins. This protein functions in DNA repair and apoptosis and is involved in signal transduction. Alternative splicing results in multiple transcript variants. (RefSeq, Jul 2008) |
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