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ELK Biotechnology TIP60 (phospho Ser86) rabbit pAb
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TIP60 (phospho Ser86) rabbit pAb는 인산화된 Ser86 부위를 인식하는 항체로, WB, ELISA, IHC에 적합합니다. 인간 및 생쥐 시료에 반응하며, 핵 및 세포질 내 TIP60 단백질의 위치 및 발현 연구에 유용합니다. 장기 보관은 -20°C에서 가능합니다.
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ELK Biotechnology ES4495-100UL TIP60 (phospho Ser86) rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES4495-50UL TIP60 (phospho Ser86) rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology TIP60 (phospho Ser86) rabbit pAb
TIP60 (phospho Ser86) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | TIP60 (phospho Ser86) rabbit pAb |
| Alternative Names | KAT5; HTATIP; TIP60; Histone acetyltransferase KAT5; 60 kDa Tat-interactive protein; Tip60; Histone acetyltransferase HTATIP; HIV-1 Tat interactive protein; Lysine acetyltransferase 5; cPLA(2)-interacting protein |
| Applications | WB; ELISA; IHC |
| Recommended Dilutions | WB 1:500–2000; IHC-p 1:50–300; ELISA 1:2000–20000 |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TIP60 around the phosphorylation site of Ser86. AA range: 52–101 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 65 kDa |
| Gene ID (Human) | 10524 |
| Human Swiss-Prot No. | Q92993 |
| Species Reactivity | Human; Mouse |
| Cellular Localization | Nucleus; Chromosome; Cytoplasm; Chromosome (centromere, kinetochore); Cytoplasm (cytoskeleton, spindle pole); Nucleus (nucleolus); Cytoplasm (perinuclear region). Upon stimulation with EDN1, exported from the nucleus to the perinuclear region; UV irradiation induces translocation into nuclear bodies (PubMed:11262386). Transiently localizes to kinetochores in early mitosis (PubMed:26829474) and spindle poles during metaphase (PubMed:34608293). Localizes in the cytoplasm and nucleus of round spermatids (By similarity). |
Background
The protein encoded by this gene belongs to the MYST family of histone acetyltransferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription, and other nuclear processes by acetylating histone and non-histone proteins. This protein functions as a histone acetylase involved in DNA repair and apoptosis, and is thought to play a key role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [Provided by RefSeq, Jul 2008]
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