ELK Biotechnology GDF-6 rabbit pAb
GDF-6 rabbit pAb는 인간, 생쥐, 랫트에서 반응하는 다클론 항체로, WB 및 ELISA에 적합합니다. 인간 GDF6 내부 영역(AA311-360)에서 유래한 합성 펩타이드로 면역화되었습니다. TGF-beta 신호전달 관련 단백질 연구에 유용하며, -20°C에서 1년 보관 가능합니다.
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제품명
GDF-6 rabbit pAb
기본 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | GDF6; GDF16; Growth/differentiation factor 6; GDF-6; Growth/differentiation factor 16 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from the internal region of human GDF6 (AA range: 311-360) |
| Species Reactivity | Human; Mouse; Rat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 50 kD |
| GeneID (Human) | 392255 |
| Human Swiss-Prot No | Q6KF10 |
| Cellular Localization | Secreted |
| Storage | -20°C / 1 year |
| Host Species | Rabbit |
Background
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene are associated with Klippel-Feil syndrome, microphthalmia, and Leber congenital amaurosis. [provided by RefSeq, Sep 2016]
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