
ELK Biotechnology CD53 rabbit pAb
CD53 rabbit pAb는 인간, 마우스, 랫트 시료에 반응하는 다클론 항체로, Western blot과 ELISA에 적합합니다. 세포막 단백질 CD53을 인식하며, 세포 성장 및 면역 반응 연구에 활용됩니다. -20°C에서 1년 보관 가능.
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- ES4321-xxxxx (2개 옵션)
- 판매단위
- pk
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제품명
CD53 rabbit pAb
주요 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | CD53; MOX44; TSPAN25; Leukocyte surface antigen CD53; Cell surface glycoprotein CD53; Tetraspanin-25; Tspan-25; CD53 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from the internal region of human CD53 (AA range: 91–140) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 24 kD |
| GeneID (Human) | 963 |
| Human Swiss-Prot No | P19397 |
| Cellular Localization | Cell membrane; Cell junction; Multi-pass membrane protein. Concentrates in microdomains along the plasma membrane at contact sites between fused myotubes. |
| Species Reactivity | Human; Mouse; Rat |
Background
The protein encoded by this gene belongs to the transmembrane 4 superfamily (tetraspanin family). Members of this family are cell-surface proteins characterized by four hydrophobic domains. These proteins mediate signal transduction events involved in cell development, activation, growth, and motility. CD53 is a cell surface glycoprotein that complexes with integrins and contributes to CD2-generated signal transduction in T cells and natural killer cells. It may play a role in growth regulation. Familial deficiency of CD53 is linked to immunodeficiency associated with recurrent bacterial, fungal, and viral infections. Alternative splicing results in multiple transcript variants.
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