Thermo Fisher Scientific MAP2K4 Polyclonal Antibody
Zebrafish MAP2K4 단백질을 인식하는 Rabbit Polyclonal 항체. Western blot에 적합하며, KLH 결합 합성 펩타이드로 면역화됨. Protein A 및 항원 친화 크로마토그래피로 정제. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Zebrafish |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 258–287 amino acids from the C-terminal region of Zebrafish Map2k4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2901051 |
Target Information
MAP2K4 (MEK4) serine/threonine kinase (mitogen-activated protein kinase 4) is a dual specificity kinase of the STE7 family that phosphorylates and activates JNK1 and JNK2 as well as p38.
MAP2K4 preferentially phosphorylates the tyrosine residue of JNKs and mediates various physiological and pathophysiological processes such as responses to cellular stresses and inflammatory cytokines.
MAP2K4 is important in carcinogenesis; loss-of-function mutations have been found in lung and pancreatic tumors, while a pro-oncogenic role has also been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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