Thermo Fisher Scientific DUSP5 Polyclonal Antibody
Human DUSP5 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 ELISA에 적합합니다. 고순도의 Affinity Chromatography 정제 제품이며, PBS/glycerol buffer로 안정화되어 있습니다. 연구용으로 ERK1 조절 관련 신호전달 연구에 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 315–384 of human DUSP5 (NP_004410.3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.94 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855078 |
Product Specific Information
Immunogen sequence:
SEILPSTPNP QPPSCQGEAA GSSLIGHLQT LSPDMQGAYC TFPASVLAPV PTHSTVSELS RSPVATATSC
Target Information
The protein encoded by this gene belongs to the dual specificity protein phosphatase (DUSP) subfamily. These phosphatases inactivate their target kinases by dephosphorylating both phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which are associated with cellular proliferation and differentiation.
Different members of this subfamily exhibit distinct substrate specificities, tissue distribution, subcellular localization, and expression inducibility. DUSP5 specifically inactivates ERK1, is expressed in multiple tissues (highest in pancreas and brain), and is localized in the nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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