Thermo Fisher Scientific GW182 Polyclonal Antibody
Rabbit polyclonal antibody recognizing GW182 (TNRC6A) protein. Verified for WB and IHC applications. Reacts with human and mouse. Lyophilized form, reconstitutable in sterile water. Suitable for research on RNA interference and microRNA pathways.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:2,000 |
| Immunohistochemistry (IHC) | 1:300–1:2,000 |
| Miscellaneous PubMed (Misc) | – |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from amino acid region 2–50 of mouse GW182 autoantigen conjugated to an immunogenic carrier protein. The peptide is homologous in human. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4 °C for short term. For long-term storage, store at −20 °C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: GW182.
Target Information
Gene/Protein: TNRC6A (GW182)
TNRC6A belongs to the trinucleotide repeat containing 6 protein family. It functions in post-transcriptional gene silencing through RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing.
Publication Note: This RefSeq record includes a subset of publications available for this gene. Please refer to the Entrez Gene record for additional references.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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