
Thermo Fisher Scientific MTHFR Monoclonal Antibody (OTI2H3), TrueMAB
MTHFR 단백질을 인식하는 Mouse monoclonal antibody로, Western blot에 최적화되어 있습니다. Human 시료에 반응하며, 1:250–1:500 희석 비율로 사용 가능합니다. Affinity chromatography로 정제되었으며, -20°C에서 보관합니다.
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Applications
- Western Blot (WB): 1:250–1:500 희석 비율 권장
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–230 of human MTHFR produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer, and acute leukemia. Mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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