Thermo Fisher Scientific PTX3 Polyclonal Antibody
PTX3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF에 사용 가능. 인간 및 마우스 반응성, 고순도 친화 크로마토그래피 정제. PBS 기반 용액 형태로 -20°C 보관.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PTX3 (Accession P26022), corresponding to amino acid residues L7–D57 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850541 |
Product Specific Information
This antibody detects endogenous levels of total PTX3.
Target Information
Pentraxins are a protein superfamily characterized by a cyclic multimeric structure. PTX3, also known as tumor necrosis factor-stimulated gene sequence-14 (TSG14), is a secreted pattern-recognition receptor involved in resistance to selected microbial agents. It belongs to the family of long pentraxins, which have C-terminal pentraxin domains and novel amino-terminal domains.
PTX3 binds pathogens such as Aspergillus fumigatus, Pseudomonas aeruginosa, and Salmonella typhimurium. It is synthesized in IgA glomerulonephritis and activates mesangial cells. Secretion in adipose cells can be induced by TNF. PTX3 plays roles in amplification of inflammatory reactions and regulation of innate immunity.
The human PTX3 gene maps to chromosome 3q25.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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