Thermo Fisher Scientific gp100/Melanosome/PMEL17/SILV (Melanoma Marker) Monoclonal Antibody (HMB45)
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멜라닌세포 종양 표지자인 gp100/PMEL17/SILV를 인식하는 HMB45 단클론 항체. 인간 시료에서 반응하며, IHC, WB, ICC/IF, Flow Cytometry 등에 사용 가능. Protein A/G 정제, 4°C 보관, 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2–4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HMB45 |
| Immunogen | Extract of pigmented melanoma metastases from lymph nodes |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Does not react with Dog or Rat.
Target Information
Melanoma is a malignant tumor of melanocytes, which are found predominantly in skin but also in the bowel and the eye (see uveal melanoma).
It is one of the rarer types of skin cancer but causes the majority of skin cancer-related deaths.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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