Thermo Fisher Scientific NAPEPLD Monoclonal Antibody (OTI1H4), TrueMAB
인간 NAPEPLD 단백질을 인식하는 Mouse IgG1 단클론 항체. Western blot 및 Immunocytochemistry에 사용 가능. 고순도의 Affinity chromatography 정제 제품으로 0.94 mg/mL 농도. PBS, BSA, glycerol 기반 저장 버퍼로 -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H4 |
| Immunogen | Full length human recombinant protein of human NAPEPLD produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.94 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
N-Acylphosphatidylethanolamine (NAPE)-hydrolyzing phospholipase D (NAPE-PLD) is a membrane-bound enzyme that releases the endocannabinoid anandamide and other bioactive N-acylethanolamines from their corresponding NAPEs in animal tissues.
NAPE-PLD is expressed by specific populations of neurons in the brain and targeted to axonal processes. Recent studies suggest that NAEs generated by NAPE-PLD in axons may act as anterograde synaptic signaling molecules regulating postsynaptic neuron activity.
Additionally, NAPE-PLD catalyzes the hydrolysis of NAPE to generate OEA (oleoylethanolamide), a natural lipid amide that inhibits food intake in rodents by prolonging latency to feed and postmeal interval.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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