Thermo Fisher Scientific Gephyrin Polyclonal Antibody
Rabbit polyclonal antibody targeting Gephyrin for WB and IHC applications. Reacts with human, mouse, and rat. Lyophilized form, reconstitutable in DDW. Affinity purified, supplied in PBS with BSA and sodium azide. Ideal for neuronal protein research.
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- AIP-005-xxxxx (3개 옵션)
- 판매단위
- pk
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Thermo Fisher Scientific Gephyrin Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:200 | |
| Immunohistochemistry (IHC) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)RDAIVKVKEVHDE, corresponding to amino acid residues 183–195 of rat Gephyrin, Intracellular |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.85 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitution: Add 25 µL, 50 µL, or 0.2 mL double distilled water (DDW), depending on sample size.
The antibody ships as a lyophilized powder at room temperature.
Upon arrival, store at -20°C.
The reconstituted solution can be stored at 4°C for up to 1 week.
For longer storage, aliquot and freeze at -20°C.
Avoid repeated freeze/thaw cycles.
Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
Gephyrin is a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high-affinity binding to receptor subunit domains and tubulin dimers.
In non-neuronal tissues, the encoded protein is required for molybdenum cofactor biosynthesis.
Mutations in this gene may be associated with hyperplexia and molybdenum cofactor deficiency.
Numerous alternatively spliced transcript variants encoding different isoforms have been described, though not all are fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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